Agilent provides xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.
Automated microscopy and Spatial Proteomics
Automated microscopy and image analysis
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Theranostics: From Mice to Men and Back
Jun 25, 2024
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Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert
Automated Purification of Viral DNA and RNA from Biological Samples usingZymo Research Quick-DNA/RNA
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The Quick DNA/RNA Viral MagBead Kit from Zymo has been automated with the Cybio FeliX pipetting robot from Analytik...
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The precision of temperature control, efficient heating and cooling rates, and excellent temperature homogeneity across...
X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization
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Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...
High-frequency Ultrasound System For Preclinical Imaging
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The Prospect T1 is an innovative high-frequency ultrasound system designed specifically for in vivo preclinical imaging...
April 2024 publication revealing benefits of using intravital microscopy in trascriptomics studies
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Transcriptional activation of Bmal1 drives the inflammatory activity of monocytes by modulating mitochondrial unfolded...
Omics Studies of Tumor Cells under Microgravity Conditions
May 6, 2024
It is important for the analysis of data from space experiments to distinguish unspecific stress reactions from...
Column-Free CD14+ Monocyte Isolation using 50nm Superparamagentic Beads on MARS® Bar
Apr 25, 2024
The MARS® Bar Magnetic Separation Platform is a closed and automated isolation for cell therapy development and...
Spatial and temporal profiling of the complement system uncovered novel functions of the alternative
Apr 24, 2024
Mounting evidence implicated the classical complement pathway (CP) in normal brain development, and the pathogenesis of...
Study finds\; Plasma p-tau217, p-tau181, and NfL as early indicators of dementia risk of AD
Apr 24, 2024
Blood biomarkers showed values for predicting future cohnitive impairment. Evidence from the community-based cohort was...
Cellular impedance measurement- novel method for in-vitro investigation of drug efficacy
Sep 12, 2017
Using standard cell lines, although attractive, can lead to unexpected results and probably to important differences when investigating a drug in primary cell lines isolated from patients. The opportunity to use cells of human origin may improve the predictive value of assays in drug testing and came hand in hand with the development of innovative real-time monitoring of cellular behaviour.
xCELLigence real time cell analyser offers a label-free non-invasive manner long-term recording of cellular signals. Considering all this aspects, the aim of our research was to evaluate the impedance of the primary melanocytes isolated from excised tumours that were confirmed as cutaneous melanoma. Primary cell cultures were used for establishing the efficacy pattern of a standard cytostatic, dacarbazine.
Our goal stands for obtaining a work flow for validating specific drug’s efficacy in individual tumour cells as a mean to personalize therapy in melanoma.
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