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These presentations fit nicely into a main theme of the conference: defining strategies to enhance the function of adoptive cell therapies in the suppressive solid tumor microenvironment (TME). While many researchers have proposed the use of novel genetic circuits and cytokines to address this problem, Xcellbio’s approach relies on precise control of the cell culture environment to potentiate cell function in the hypoxic, highly pressured TME. Another hot topic at the CAR-TCR conference was the need for improved characterization and potency assays that more closely mimic a cell therapy’s mechanism of action. By enabling real time cell killing assays to be performed under TME-like conditions, the AVATAR AI provides a more physiologically relevant, and likely more predictive, readout of a therapy’s in vivo efficacy.
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Brand profile
The company provides a revolutionary cell culturing platform that replicates the physiological environment of native tissues to deliver reproducible and biologically relevant molecular analysis.
More info at:
www.xcellbio.com
