New Center of Excellence, located at the Josep Carreras Leukaemia Research Institute

As Mission Bio’s second single-cell Tapestri Center of Excellence and the first in Europe, the Josep Carreras Institute will inform academic and industrial best practices using single-cell DNA and multi-omics sequencing in hematological malignancy research, as well as a new program in breast cancer. As a leading leukemia research center in Europe, the Josep Carreras Institute has long been a champion of single-cell analysis and launched a specialized unit in 2021. Today’s partnership will further the Josep Carreras Institute’s application of single-cell DNA sequencing to investigate disease progression, therapeutic resistance, and measurable residual disease (MRD) in both blood cancers and its novel breast cancer research program. The Josep Carreras Institute is the first European research center with expertise focused on leukemia and other blood cancers. The institution’s main research focus is on identification of new therapeutic targets and development of more precise and less aggressive treatments by understanding the origin and development of leukemia and other blood cancers. Esteller, director of the Josep Carreras Institute, is the author of more than 600 original publications in peer-reviewed scientific journals. He is also the Editor-in-Chief of Epigenetics and an editorial board member of Genome Research. Last year, he co-authored an article in Experimental Hematology about the benefits of single-cell analytics to characterize the heterogeneity and clonal evolution of blood cell subpopulations in myeloid and lymphoid cancers, which can improve patient diagnosis, risk stratification and targeted therapy prescription.