Agilent provides xCELLigence impedance-based, label-free, real time cell analysis system and NovoCyte flow cytometers.
Automated microscopy and Spatial Proteomics
Automated microscopy and image analysis
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Liquid handling devices (LHD) improve lab efficiency and accuracy. They automate liquid transfers, increase experiment...
Scaling Whole-Genome Sequencing to >50,000 single cells using cellenONE
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X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization
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April 2024 publication revealing benefits of using intravital microscopy in trascriptomics studies
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Omics Studies of Tumor Cells under Microgravity Conditions
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Column-Free CD14+ Monocyte Isolation using 50nm Superparamagentic Beads on MARS® Bar
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Preclinical cardiac safety assessment using xCELLigence Cardio
Apr 21, 2016
Most of the drugs that have been withdrawn from the market due to cardiotoxicity appear to affect heart function by directly interfering with well-coordinated electrical activity in the heart.The electrical activity of the heart itself results from directional and selective movement of calcium, sodium, and potassium ions across channels in the membrane of cardiomyocytes; this movement couples with the specialized cytoskeleton to produce contraction and the force necessary for the pumping action of the heart. Interfering with this well-orchestrated movement of ions across the cardiomyocyte membrane can lead to electrical arrhythmia that will ultimately affect the excitation/contraction coupling cycle of the heart and may lead to a life-threatening form of ventricular arrhythmia called Torsades de Pointes (TdP).
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