Discover
Related topics
Don't waste your time for homogenization and get best results in neurscience with Singulator!
Jan 6, 2025
Single-nuclei sequencing (SNS) is a transformative approach for dissecting cellular diversity in complex tissues like...
Get your cells ready for NGS with tiples nanodispenser MANTIS
Jan 6, 2025
Generating high-quality cDNA libraries for efficient sequencing of T-cell receptor mRNA from single cells.
Study finds that automated liquid-handling operations are more robust, resilient, and efficient!
Jul 18, 2024
Liquid handling devices (LHD) improve lab efficiency and accuracy. They automate liquid transfers, increase experiment...
Scaling Whole-Genome Sequencing to >50,000 single cells using cellenONE
Jul 16, 2024
cellenONE technology enabled the creation of tens of thousands of high-quality single-cell genomes, paving the way for...
Theranostics: From Mice to Men and Back
Jun 25, 2024
Recorded webinar
Presenters: Prof. Dr. Ken Herrmann and Prof. Dr. Katharina Lückerath – Moderator: Hannah Notebaert
Automated Purification of Viral DNA and RNA from Biological Samples usingZymo Research Quick-DNA/RNA
Jun 14, 2024
The Quick DNA/RNA Viral MagBead Kit from Zymo has been automated with the Cybio FeliX pipetting robot from Analytik...
DNA Amplicon Library Preparation for Illumina® Sequencing
Jun 12, 2024
The precision of temperature control, efficient heating and cooling rates, and excellent temperature homogeneity across...
X-RAD 320 for irradiation therapy during quantifying study for in vivo collagen reorganization
Jun 5, 2024
Quantifying in vivo collagen reorganization during immunotherapy in murine melanoma with second harmonic generation...
High-frequency Ultrasound System For Preclinical Imaging
May 13, 2024
The Prospect T1 is an innovative high-frequency ultrasound system designed specifically for in vivo preclinical imaging...
April 2024 publication revealing benefits of using intravital microscopy in trascriptomics studies
May 7, 2024
Transcriptional activation of Bmal1 drives the inflammatory activity of monocytes by modulating mitochondrial unfolded...
Mar 2, 2017
Here we have characterized gene-trap mice lacking Tspan9. The mice were viable with normal platelet numbers and size. Tspan9-deficient platelets were specifically defective in aggregation and secretion induced by the platelet collagen receptor GPVI, despite normal surface GPVI expression levels. A GPVI activation defect was suggested by partially impaired GPVI-induced protein tyrosine phosphorylation. In mechanistic experiments, Tspan9 and GPVI co-immunoprecipitated and co-localised, but super-resolution imaging revealed no defects in collagen-induced GPVI clustering on Tspan9-deficient platelets. However, single particle tracking using total internal reflection fluorescence microscopy showed that GPVI lateral diffusion was reduced by approximately 50% in the absence of Tspan9. Therefore, Tspan9 plays a fine-tuning role in platelet activation by regulating GPVI membrane dynamics.
Brand profile
With BioFlux System for live cell analysis under shear flow and IsoFlux System for circulating tumor cell analysis, Cell Microsystems turn power of benchtop cellular analysis with advanced tools to automate complex assays.
More info at:
https://cellmicrosystems.com
