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Serum neurofilament measurement improves clinical risk scores for outcome prediction.

Serum neurofilament measurement improves clinical risk scores for outcome prediction.

Admission NfL was a strong outcome predictor and significantly improved two clinical risk scores regarding prognostication of neurological outcome in patients after cardiac arrest. When confirmed in future outcome studies, admission NfL should be considered as a standard laboratory measures in the evaluation of OHCA patients.

Related technologies: Digital biomarker detection

Katarzyna Nazarewicz

Katarzyna Nazarewicz

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Simoa technology is changing the way in which the biology of health and disease is studied by giving researchers the ability to closely examine critical biomarkers.

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A recent study found serum neurofilament light chain (NfL) levels to be strongly associated with poor neurological outcome in patients after cardiac arrest. Our aim was to confirm these findings in an independent validation study.

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