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Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice.

Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice.

Transfer and labeling studies demonstrated that ABCs are dynamic, rapidly turning over. scRNA-seq identified B cell clones present in multiple subsets, revealing that ABCs can be plasmablast precursors or undergo cycles of reactivation. Deletion of CD11c-expressing B cells revealed a direct role for ABC-like B cells in lupus pathogenesis.

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Katarzyna Nazarewicz

Katarzyna Nazarewicz

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Cytek Biosciences

Cytek provides compact and affordable flow cytometry instruments with multiplexing capability that streamlines workflows and delivers a high level of biological clarity for a majority of applications.

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A prodigy that takes flow cytometry to the next level, with up to five lasers and 64 fluorescence channels.

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