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Serum neurofilament measurement improves clinical risk scores for outcome prediction.
A recent study found serum neurofilament light chain (NfL) levels to be strongly associated with poor neurological outcome in patients after cardiac arrest. Our aim was to confirm these findings in an independent validation study.
April 16, 2025
High-throughput, physiological assays of leukocyte adhesion and rolling
BioFlux shear flow systems enable the visualization and analysis of all of the steps of the leukocyte adhesion cascade under physiological/pathological shear flow using one system.
April 4, 2025
A comprehensive comparison on clustering methods for multi-slide spatially resolved transcriptomics
This study evaluates clustering methods for multi-slide spatial transcriptomics (ST) data, analyzing preprocessing techniques like PASTE and Harmony to guide method selection.
March 19, 2025
Change in Enlarged Perivascular Spaces over Time and Associations with Outcomes After Brain Injury
The goal of this study was to identify MRI burden of EPVs over time following TBI and to explore their relationship with postinjury outcomes.
March 3, 2025
Preclinical SPECT and PET: Joint EANM and ESMI procedure guideline 2024
The aim of this guideline is to provide recommendations for the implementation of an effective and efficient quality control (QC) program for SPECT and PET systems in a preclinical imaging lab. Published online: 15 July 2024
February 6, 2025
Single-Cell Identification of multiple myeloma MM clones – NGS
Preview of an upcoming single-cell multi-omics assay that uncovers complex clonal heterogeneity underlying myeloma evolution and biology, and novel data identifying the clonal populations that progress to active MM or resistant disease.
August 21, 2024
Protocol for simultaneous isolation of high-quality & high-quantity cardiomyocytes and non-myocytes
A protocol to simultaneously isolate high-quality and high-quantity cardiomyocytes and non-myocyte cells, including immune cells, from adult rat hearts. Detailed procedures for viability analysis and cell type identification using Wolf sorter.
March 28, 2025
Optimizing Substrate Dosing for Reliable Bioluminescence Imaging (BLI)
Best Practices for Substrate Dosing: dose based on weight, prepare fresh solutions, use standardized routes of administration and more
March 17, 2025
1568 Single-Cell Multi-Omic Analysis of AML MRD Reveals Differences in Clonal Architecture
The Mission Bio AML single-cell MRD assay quantitatively characterizes SNVs and surface protein expression simultaneously across thousands of individual cells. In contrast, bulk NGS requires averaging across the entire population.
February 28, 2025
Don’t waste your time for homogenization and get best results in neurscience with Singulator!
Single-nuclei sequencing (SNS) is a transformative approach for dissecting cellular diversity in complex tissues like the brain. Effective isolation of high-quality cells with intact nuclei is essential for the success of this technique.
January 6, 2025
Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice.
Here we report, in the MRL/lpr SLE model, unexpected heterogeneity among ABC-like cells for expression of the integrins CD11b and CD11c, T-bet, and memory or plasmablast markers.
March 21, 2025
Maximize results and efficiency of Analytik Jena equipment in your NGS workflow with new ebook
This e-book shows how important NGS sample preparation is for high-quality sequencing results and how it can be simplified and optimized.
March 4, 2025
Francisella tularensis induces Th1 like MAIT cells conferring protection against infection
F. tularensis LVS activates MAIT reporter cells in vitro in an MR1-dependent manner and induces a systemic MAIT cell response in vivo.
February 27, 2025
Get your cells ready for NGS with tiples nanodispenser MANTIS
Generating high-quality cDNA libraries for efficient sequencing of T-cell receptor mRNA from single cells.
January 6, 2025