Intravital imaging offers a unique window into these dynamic processes, enabling researchers to visualize blood flow, thrombus formation, immune cell responses, and changes in the cardiac microenvironment in real time.
This note demonstrates a UVA-based Thermal Shift Assay on the qTOWER iris, enabling sensitive detection of protein stability and expanding qPCR use to protein analysis.
The standardized and automatic handling of cryopreserved biological samples plays an increasingly important role in today’s in vitro testing. This is due to the trend to develop more complex disease models to increase the data quality of studies.
MOLECUBES β-CUBE and X-CUBE were used to investigate the ability of [18F]-TMP, a newly developed fluorine-18 probe, to image primary human chimeric antigen receptor (CAR) T cells expressing the PET reporter gene eDHFR.
Combining IP-MS with Syncell optoproteomics reveals how the NLRP3 inflammasome dynamically reorganizes its protein interaction network and identifies a novel regulatory mechanism.
mRNA vaccine efficacy is enhanced by preventing expression in hepatocytes rather than promoting it in dendritic cells. The findings highlight tissue-specific targeting as a potential strategy for improving vaccines and cancer immunotherapies.
This application note presents a rapid, automated DNA purification workflow using the CyBio FeliX system with sbeadex Lightning technology, enabling high-quality results in just minutes while reducing hands-on time and increasing throughput.
Explore how Microscoop® enables spatially resolved nuclear and cytoplasmic proteomics, delivering reproducible, high-specificity subcellular protein profiling through microscopy-guided photolabeling and mass spectrometry.
Automated membrane protein purification with CyBio FeliX and NativeMP™ reduces processing time to under three hours while preserving protein integrity and ensuring high reproducibility.
This application note presents a rapid, automated DNA purification workflow using the CyBio FeliX system with sbeadex Lightning technology, enabling high-quality results in just minutes while reducing hands-on time and increasing throughput.
This study investigates the subnuclear organization of the Polycomb repressive complex 2 (PRC2) in triple-negative breast cancer (TNBC) cells, combining in situ proteomics, high-resolution imaging, and functional genomics.