Discover
Generating High-Quality cDNA Libraries for Efficient Sequencing of T-cell Receptor mRNA
Single-cell omics provide undiluted information about individual cells, such as transcription levels and sequences of highly variable proteins.Miniaturizing the assay helps scale down analysis to the single-cell level without sacrificing data quality
July 2, 2025
Incorporation of SARS-CoV-2 spike NTD to RBD protein vaccine improves immunity against viral variant
By fusing the spike protein's terminal domain (NTD) with its receptor-binding domain (RBD), researchers have engineered a protein vaccine that significantly amplifies both T-cell responses and antibody breadth.
June 25, 2025
Differential diagnostic performance of a panel of plasma biomarkers for different types of dementia
This study assesses a plasma biomarker panel (p-tau181, NfL, GFAP) for differentiating Alzheimer’s, FTD, and DLB, showing high accuracy, while Aβ₁₋₄₂/₁₋₄₀ ratio adds limited value.
June 9, 2025
Control of behavioral uncertainty by divergent frontal circuits
Preprint on bioRxiv shows that plasma p-tau181, NfL, and GFAP effectively differentiate Alzheimer’s from FTD and DLB, while Aβ₁₋₄₂/₁₋₄₀ adds little diagnostic value.
June 4, 2025
Single-cell DNA and surface protein characterization of high hyperdiploid acute leukemia
Single-cell DNA and surface protein characterization of high hyperdiploid acute lymphoblastic leukemia at diagnosis and during treatment
May 7, 2025
Serum neurofilament measurement improves clinical risk scores for outcome prediction.
A recent study found serum neurofilament light chain (NfL) levels to be strongly associated with poor neurological outcome in patients after cardiac arrest. Our aim was to confirm these findings in an independent validation study.
April 16, 2025
Growing Mature Biofilms for Antimicrobial Screening, Host-pathogen Interactions, and Adhesion
We present the BioFlux shear flow system, a microfluidic flow cell array that enables the growth of biofilms in precisely controlled conditions, including shear stress, temperature, and environmental gas.
June 18, 2025
Spatial Proteomics: Charting the Protein Landscape in Tissues
Spatial proteomics uncovers the spatial distribution of proteins within tissues, enabling detailed analysis of cellular functions, disease progression, and intercellular interactions beyond the limits of traditional bulk proteomic approaches.
June 6, 2025
How to Make Membrane Protein Research Less Frustrating?
What if studying membrane proteins didn’t have to be so hard? Discover how a breakthrough technique is making fragile, complex proteins easier to analyze — no purification, no immobilization, just real results.
June 3, 2025
Optimized rare cell isolation for mouse and human samples
This application note introduces the new in situ rinse program. This workflow delivers the same high purity of rare cells as the traditional “serial program” and additionally significantly enhances throughput.
April 29, 2025
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors
Analysis of the human hematopoietic progenitor compartment is being transformed by single-cell multimodal approaches.
April 15, 2025
IsoSpark in HIV research: quantitation of proteins in the culture supernatants.
Exciting example of use 22-plex antibody with the IsoPlexis Human Adaptive Immune Panel (Bruker Cellular Analysis) in HIV research.
June 12, 2025
Integrated Biomarker Discovery and T Cell Analysis using the IsoSpark and Beacon Platforms
Bruker’s proteomic barcode and optofluidic technologies synergize to provide researchers with comprehensive understanding of T cell biology.
June 5, 2025
Curious how PET imaging and reporter gene tracking are transforming CAR-T cell therapy in oncology?
Recorded webinar is recommended if you are working or you are interested by translational studies in oncology, immune therapy, and biomedical imaging.
June 2, 2025
Advanced spatial biology sheds new light on therapeutic research
See how high-resolution multiplex immunofluorescence imaging can elucidate the important role the immune system plays in health, disease, and drug development.
April 22, 2025