Discover
Whole genome analysis and in vivo safety assessment of probiotic candidate Lactobacillus acidophilus
Probiotics, particularly strains of lactic acid bacteria (LAB), are recognized for their beneficial effects on gut health. Lactobacillus acidophilus L177, a promising probiotic strain isolated from canine feces, was evaluated for safety and probiotic.
March 10, 2026
Introducing IVM-FS: Real-Time Cellular Insightsinto Rats and Other Medium-Sized Animals
Rats are increasingly valued for intravital imaging due to their larger body size and organ systems, which enable more precise surgical preparation, stable window implantation, and repeated long-term imaging - advantages over mice.
March 3, 2026
CXCL12+ fibroblastic reticular cells in lymph nodes facilitate immune tolerance
The popliteal LNs were exposed surgically and confocal intravital imaging was performed (IVM-CMS3). Twenty-five Z-stack images were obtained with a 3 μm axial interval. Time-lapse images were obtained at a 1-minute time interval for 20 minutes.
January 26, 2026
The Path to Clinical Relevance: Moving from Spatial Transcriptomics to Protein Profiling
Spatial biology is a rapidly evolving discipline that advances human health by leveraging imaging technologies. It encompasses research activities ranging from whole-transcriptome profiling to clinically impactful single-protein biomarker tests.
December 2, 2025
Can you solve mouse CT imaging with 50um spatial resolution ?
MOLECUBES, a Bruker Company offers small footprint microCT for mice and rats, which meets most of your needs for in-vivo analysis and doesn't sacrifice the budget.
October 22, 2025
Refining Biomedical Research Beyond Animal Models
What the Pivot to Human-Based Technologies Means for Science and How 3D Cellular Constructs like Organoids Are Part of the Solution.
October 13, 2025
Combining GrowDex® and spheroONE for automated and highly reproducible 3D cell culture workflows
This application note demonstrates the compatibility of spheroONE and GrowDex® to automate 3D cell culture workflows. spheroONE is a nanoliter dispenser enabling sorting and isolation of spheroids and organoids.
February 25, 2026
Functional, Fast, and Unbiased TCR Discovery with Bruker’s Optofluidic Platform
Identifying antigen specific T-cell receptors (TCRs) is critical for advancing TCR-T therapies, vaccines, and infectious disease research. Yet, traditional peptide-MHC tetramer/dextramer sorting only tells part of the story.
January 23, 2026
Development of new albumin‑binding radiotracers for PET imaging of CSF
In this study by Peltoniemi et al., PET/CT imaging using the X-CUBE (CT) and ß-CUBE (PET) was used to non-invasively visualize cerebrospinal fluid (CSF) flow and glymphatic system dynamics in rats.
November 28, 2025
Measure EV Purity Results by Calculating the Membrane Ratio with the Exoplorer
Working with Extracellular Vesicles (EVs)? Imagine being able to effortlessly measure EV quality. This is possible with the Exoplorer™ Nano-flow Cytometer — a highly effective tool for nanoparticle-level analysis.
October 20, 2025
Optimizing Substrate Dosing for ReliableBioluminescence Imaging (BLI)
Bioluminescence imaging relies on precise D-luciferin administration, as dosing variability impacts signal intensity and data consistency. Standardizing substrate delivery is essential for reproducible and high-quality in vivo imaging results.
September 18, 2025
Comparing Microscoop® with Proximity Labeling Techniques APEX2 and BioID
Discover how Microscoop®, APEX2, and BioID offer unique advantages for mapping protein-protein interactions—whether in fixed tissue or live cells. Learn which method fits your proteomics research best!
February 23, 2026
Combination of low-energy X-ray & citric acid to inactivate E.coli, S.Typhimurium, L.Monocitogenes
Combined treatment with 0.5 kGy X-ray and 0.1 % CA significantly decreased biofilm cell counts by 5.10, 4.31, and 3.96 log CFU/coupon for E. coli O157:H7, S. Typhimurium, and L. Monocytogenes, respectively.
December 3, 2025
Perfusion: The Beating Heart of Single-Cell Biology and Cancer Immunotherapy
Single-cell biology has transformed our ability to uncover cellular diversity and dynamic behavior within complex tissues that are otherwise masked in population-level analyses.
November 24, 2025
Automated and efficient isolation of single cells into low volumes for scWGA
Single-cell whole-genome amplification (scWGA) is a powerful technique to massively amplify and analyse the genomes of individual cells.
October 17, 2025