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“XCelligence system represents very usefull and user friendly tool for monitoring of cell proliferation and migration under different treatment and conditions.”
Institute of Biophysics of the Czech Academy of Sciences
“xCELLigence system helped my research in performing real-time evaluation of the toxicological profile for several types of innovative drugs that were tested on both primary cells and standard cell lines. Additionally, this platform demonstrated high sensitivity of detection of intracellular signaling events for drugs targeting protein kinases-mediated cellular pathways.”
‘Victor Babeș’ National Institute of Pathology, Bucharest, Romania
„Our researches are mostly focused in the context of type II Diabetes, Obesity and a broad range of applications in cell biolabeling, cancer treatment, metastasis and therapeutic drug monitoring. Compared to traditonal end-point method, xCelligence system revolutionized our workflow adding real-time monitoring of cells inside incubator as an fundamental factor to assess long term effect of different compounds of interest.”
Wroclaw Medical University, Poland
“We successfully employed xCELLigence system for studying migration of malignant melanoma cell lines in response to variety of agents. We were also able to employ this system to measure the invasion of HUVEC endothelial cell monolayer by melanoma cells according to this: JOVE protocol”
Medical University of Lublin, Department of Biopharmation
“The xCELLigence RTCA DP system is an easy to use platform with intuitive software and a variety of online tutorials for beginners and experience users. It is great tool for our cell therapies development, our laboratory obtained exciting results for cytotoxicity assays using adherent and suspension cells.”
Center for gene and cellular therapies in the treatment of cancer (OncoGen), Timisoara, Romania
“xCelligence system offers unique technology that can be easily employed to measure and quantify the efficacy of cell-based immunotherapies. Indeed, we have successfully implemented protocols that enable us to monitor the efficacy of CAR T mediated cytotoxicity toward adherent breast cancer cells. The greatest advantage of the system is the real-time instead of the end-point readout. The data collected using the RTCA system fill in a common gap concerning the kinetics of the cell-based cytotoxicity process.”
WUM, Warszawa, Poland
“I used the xCELLigence DP system to study the effectiveness of CAR-T against target cancer cells. I was able to observe the effectiveness of cell therapy during the entire experiment with great accuracy. Both devices and software are easy and pleasant to use.”
Helix Immuno-Oncology, Warsaw, Poland
“The xCELLigence RTCA SP analysis is without any doubts a proven non-invasive and sensitive method for monitoring the viability, proliferation or migration of cells in real time and thus complements and explains a number of end-point experiments. Our laboratory deals with the study of new natural molecules or compounds prepared semisynthetically. The analysis software is also intuitive and complete, moreover, ACCELA as a local supplier is able to provide qualified training and service.”
Charles University, Faculty of Medicine in Hradec Kralove, Czech Republic
“By skipping the guesswork associated with end-point assays and eliminating the time- and labor-intensive steps of traditional cell-based assays, real-time cell analysis with the xCELLigence RTCA DP vastly improves efficiency and overall productivity. By eliminating the need for labels/dyes, the physiological relevance of acquired data is maximized.”
Faculty of Medicine, University of Szeged, Hungary
“The iCELLigence system provides me a fast, reliable and reproducible way to specifically monitor the suspension cell interactions with proteins of the extracellular matrix, and dynamics of its changes in response to inhibitor addition.”
Institute of Hematology and Blood Transfusion (ÚHKT)
The RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16.It is located inside a tissue culture incubator. Each of the three 16-well plate holders can be used independently under the RTCA Software. The RTCA DP Analyzer can automatically select wells for measurement and continuously transfer measured impedance data to the computer. Cell Index values, derived from the measured impedances, are continuously displayed on the Software user interface.
The RTCA DP Instrument is composed of three main components:
RTCA DP Instrument Highlights:
More info at: https://www.aceabio.com/products/rtca-dp/
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