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“xCELLigence system helped my research in performing real-time evaluation of the toxicological profile for several types of innovative drugs that were tested on both primary cells and standard cell lines. Additionally, this platform demonstrated high sensitivity of detection of intracellular signaling events for drugs targeting protein kinases-mediated cellular pathways.”

Dr Monica Neagu

‘Victor Babeș’ National Institute of Pathology, Bucharest, Romania

‘Victor Babeș’ National Institute of Pathology, Bucharest, Romania

„Our researches are mostly focused in the context of type II Diabetes, Obesity and a broad range of applications in cell biolabeling, cancer treatment, metastasis and therapeutic drug monitoring. Compared to traditonal end-point method, xCelligence system revolutionized our workflow adding real-time monitoring of cells inside incubator as an fundamental factor to assess long term effect of different compounds of interest.”

Dr Marta Kepinska

Wroclaw Medical University, Poland

Wroclaw Medical University, Poland

“The xCELLigence system proved to be a unique and invaluable technology in the development of new therapeutics for the steroid hormone sensitive cancers. It enabled us to analyze detailed proliferation dynamics of various cancer cell types, in response to manipulation of complex signaling network by steroid hormone receptors and enzymes involved in the steroid hormone biosyntesis.”

Dr David Sedlák

Institute of Molecular Genetics of the ASCR, Prague, Czech Republic

Institute of Molecular Genetics of the ASCR, Prague, Czech Republic

“I used the xCELLigence DP system to study the effectiveness of CAR-T against target cancer cells. I was able to observe the effectiveness of cell therapy during the entire experiment with great accuracy. Both devices and software are easy and pleasant to use.”

Dr Anna Bujak, Principal Research Scientist

Helix Immuno-Oncology, Warsaw, Poland

Helix Immuno-Oncology, Warsaw, Poland

“The xCELLigence RTCA SP analysis is without any doubts a proven non-invasive and sensitive method for monitoring the viability, proliferation or migration of cells in real time and thus complements and explains a number of end-point experiments. Our laboratory deals with the study of new natural molecules or compounds prepared semisynthetically. The analysis software is also intuitive and complete, moreover, ACCELA as a local supplier is able to provide qualified training and service.”

Dr Darja Koutová

Charles University, Faculty of Medicine in Hradec Kralove, Czech Republic

Charles University, Faculty of Medicine in Hradec Kralove, Czech Republic

“By skipping the guesswork associated with end-point assays and eliminating the time- and labor-intensive steps of traditional cell-based assays, real-time cell analysis with the xCELLigence RTCA DP vastly improves efficiency and overall productivity. By eliminating the need for labels/dyes, the physiological relevance of acquired data is maximized.”

Dr Veréb Zoltán

Faculty of Medicine, University of Szeged, Hungary

Faculty of Medicine, University of Szeged, Hungary

“We purchased the system as we had a good experience with it in past – our group works in the field of nanomedicine. In experiments, various nanomaterials (carbon, magnetic particles) are modified by antitumor drugs and other molecules for specific targeting of tumor cells.
The the greatest benefit of the system is that the experiments are easy to set up, the data are obtained in a relatively short time without the need for more complicated sample manipulation. The method makes it possible not only to monitor the increasing number of cells, but also to evaluate the progress of this process – to elegantly determine the growth characteristics of the studied cells and to test the substances used. The process is completely independent of the human factor, thereby minimizing common experimental errors.”

Prof. René Kizek

University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic

University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic

“xCELLigence system is helping my research with fast and reliable screening experiments on cells proliferation, migration and invasion under different cells growth conditions.”

Dr Joanna Kozak

Medical University of Lublin, Human Anatomy Department

Medical University of Lublin, Human Anatomy Department

xCELLigence HT – Agilent technologies

Real-time, label-free and automated cell-based high throughput screening

The RTCA HT Instrument can be integrated with automated liquid handling platforms or a robotic plate handler from different vendors.Up to four RTCA HT Stations can be linked to one RTCA HT Analyzer, and perform real-time, label-free cell-based assays in automated high-throughput screening.

The RTCA HT Instrument is composed of four main components:

  • RTCA HT Station
  • RTCA HT Analyzer
  • RTCA HT Control Unit
  • E-Plate 384

More info at: https://www.aceabio.com/products/rtca-ht/

Documentation

flyer-acea_ht_.pdf

Katarzyna Nazarewicz

Country manager

Katarzyna Nazarewicz

+48 797 701 027

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Located inside a tissue culture incubator, it is capable of switching any one of the wells on any of six E-Plates to the RTCA Analyzer for impedance measurement.

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Located inside a tissue culture incubator, it is capable of switching any one of the wells on the E-Plate 96 to the RTCA Analyzer for impedance measurement.

show detail

xCELLigence SP – Agilent technologies