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“xCELLigence system helped my research in performing real-time evaluation of the toxicological profile for several types of innovative drugs that were tested on both primary cells and standard cell lines. Additionally, this platform demonstrated high sensitivity of detection of intracellular signaling events for drugs targeting protein kinases-mediated cellular pathways.”
‘Victor Babeș’ National Institute of Pathology, Bucharest, Romania
„Our researches are mostly focused in the context of type II Diabetes, Obesity and a broad range of applications in cell biolabeling, cancer treatment, metastasis and therapeutic drug monitoring. Compared to traditonal end-point method, xCelligence system revolutionized our workflow adding real-time monitoring of cells inside incubator as an fundamental factor to assess long term effect of different compounds of interest.”
Wroclaw Medical University, Poland
“The xCELLigence system proved to be a unique and invaluable technology in the development of new therapeutics for the steroid hormone sensitive cancers. It enabled us to analyze detailed proliferation dynamics of various cancer cell types, in response to manipulation of complex signaling network by steroid hormone receptors and enzymes involved in the steroid hormone biosyntesis.”
Institute of Molecular Genetics of the ASCR, Prague, Czech Republic
“The xCELLigence RTCA DP system is an easy to use platform with intuitive software and a variety of online tutorials for beginners and experience users. It is great tool for our cell therapies development, our laboratory obtained exciting results for cytotoxicity assays using adherent and suspension cells.”
Center for gene and cellular therapies in the treatment of cancer (OncoGen), Timisoara, Romania
“I used the xCELLigence DP system to study the effectiveness of CAR-T against target cancer cells. I was able to observe the effectiveness of cell therapy during the entire experiment with great accuracy. Both devices and software are easy and pleasant to use.”
Helix Immuno-Oncology, Warsaw, Poland
“The xCELLigence RTCA SP analysis is without any doubts a proven non-invasive and sensitive method for monitoring the viability, proliferation or migration of cells in real time and thus complements and explains a number of end-point experiments. Our laboratory deals with the study of new natural molecules or compounds prepared semisynthetically. The analysis software is also intuitive and complete, moreover, ACCELA as a local supplier is able to provide qualified training and service.”
Charles University, Faculty of Medicine in Hradec Kralove, Czech Republic
“By skipping the guesswork associated with end-point assays and eliminating the time- and labor-intensive steps of traditional cell-based assays, real-time cell analysis with the xCELLigence RTCA DP vastly improves efficiency and overall productivity. By eliminating the need for labels/dyes, the physiological relevance of acquired data is maximized.”
Faculty of Medicine, University of Szeged, Hungary
“We purchased the system as we had a good experience with it in past – our group works in the field of nanomedicine. In experiments, various nanomaterials (carbon, magnetic particles) are modified by antitumor drugs and other molecules for specific targeting of tumor cells.
The the greatest benefit of the system is that the experiments are easy to set up, the data are obtained in a relatively short time without the need for more complicated sample manipulation. The method makes it possible not only to monitor the increasing number of cells, but also to evaluate the progress of this process – to elegantly determine the growth characteristics of the studied cells and to test the substances used. The process is completely independent of the human factor, thereby minimizing common experimental errors.”
University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic
“xCELLigence system is helping my research with fast and reliable screening experiments on cells proliferation, migration and invasion under different cells growth conditions.”
Medical University of Lublin, Human Anatomy Department
The RTCA MP Station is located inside a tissue culture incubator and is capable of switching any one of the wells on any of six E-Plates to the RTCA Analyzer for impedance measurement.Each of the six E-Plate holders can be used independently under the RTCA Software. The RTCA Analyzer can automatically select wells for measurement and continuously transfer measured impedance data to the computer. Cell Index values, derived from the measured impedances, are continuously displayed on the Software user interface.
The RTCA MP Instrument is composed of four main components:
RTCA MP Instrument Highlights:
More info at: https://www.aceabio.com/products/rtca-mp/
Documentation