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“xCELLigence system helped my research in performing real-time evaluation of the toxicological profile for several types of innovative drugs that were tested on both primary cells and standard cell lines. Additionally, this platform demonstrated high sensitivity of detection of intracellular signaling events for drugs targeting protein kinases-mediated cellular pathways.”

Dr Monica Neagu

‘Victor Babeș’ National Institute of Pathology, Bucharest, Romania

‘Victor Babeș’ National Institute of Pathology, Bucharest, Romania

„Our researches are mostly focused in the context of type II Diabetes, Obesity and a broad range of applications in cell biolabeling, cancer treatment, metastasis and therapeutic drug monitoring. Compared to traditonal end-point method, xCelligence system revolutionized our workflow adding real-time monitoring of cells inside incubator as an fundamental factor to assess long term effect of different compounds of interest.”

Dr Marta Kepinska

Wroclaw Medical University, Poland

Wroclaw Medical University, Poland

“I used the xCELLigence DP system to study the effectiveness of CAR-T against target cancer cells. I was able to observe the effectiveness of cell therapy during the entire experiment with great accuracy. Both devices and software are easy and pleasant to use.”

Dr Anna Bujak, Principal Research Scientist

Helix Immuno-Oncology, Warsaw, Poland

Helix Immuno-Oncology, Warsaw, Poland

“The xCELLigence RTCA SP analysis is without any doubts a proven non-invasive and sensitive method for monitoring the viability, proliferation or migration of cells in real time and thus complements and explains a number of end-point experiments. Our laboratory deals with the study of new natural molecules or compounds prepared semisynthetically. The analysis software is also intuitive and complete, moreover, ACCELA as a local supplier is able to provide qualified training and service.”

Dr Darja Koutová

Charles University, Faculty of Medicine in Hradec Kralove, Czech Republic

Charles University, Faculty of Medicine in Hradec Kralove, Czech Republic

“By skipping the guesswork associated with end-point assays and eliminating the time- and labor-intensive steps of traditional cell-based assays, real-time cell analysis with the xCELLigence RTCA DP vastly improves efficiency and overall productivity. By eliminating the need for labels/dyes, the physiological relevance of acquired data is maximized.”

Dr Veréb Zoltán

Faculty of Medicine, University of Szeged, Hungary

Faculty of Medicine, University of Szeged, Hungary

“The iCELLigence system provides me a fast, reliable and reproducible way to specifically monitor the suspension cell interactions with proteins of the extracellular matrix, and dynamics of its changes in response to inhibitor addition.”

Dr Adam Obr

Institute of Hematology and Blood Transfusion (ÚHKT)

Institute of Hematology and Blood Transfusion (ÚHKT)

“We purchased the system as we had a good experience with it in past – our group works in the field of nanomedicine. In experiments, various nanomaterials (carbon, magnetic particles) are modified by antitumor drugs and other molecules for specific targeting of tumor cells.
The the greatest benefit of the system is that the experiments are easy to set up, the data are obtained in a relatively short time without the need for more complicated sample manipulation. The method makes it possible not only to monitor the increasing number of cells, but also to evaluate the progress of this process – to elegantly determine the growth characteristics of the studied cells and to test the substances used. The process is completely independent of the human factor, thereby minimizing common experimental errors.”

Prof. René Kizek

University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic

University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic

“xCELLigence system is helping my research with fast and reliable screening experiments on cells proliferation, migration and invasion under different cells growth conditions.”

Dr Joanna Kozak

Medical University of Lublin, Human Anatomy Department

Medical University of Lublin, Human Anatomy Department

xCELLigence SP – Agilent technologies

Basic tool with a huge impact for any cell based assay

The RTCA SP Station is located inside a tissue culture incubator and is capable of switching any one of the wells on the E-Plate 96 to the RTCA Analyzer for impedance measurement. Under the software of the RTCA Control Unit, the RTCA SP Analyzer can automatically select wells for measurement and continuously transfer measured impedance data to the computer. Cell Index values, derived from the measured impedances, are continuously displayed on the Software user interface.

The RTCA SP Instrument is composed of four main components:

  • RTCA Analyzer
  • RTCA SP Station
  • RTCA Control Unit
  • E-Plate 96

RTCA SP Instrument Highlights:

  • Rapid measurement time – less than 10 or 60 seconds for 96 wells
  • Compact design of the RTCA SP Station that fits conveniently in tissue culture incubators
  • High-performance electronic components and enhanced instrument reliability
  • Easy setup and customization of assay protocols
  • Integrated, on-line data analysis capability

More info at: https://www.aceabio.com/products/rtca-sp/

Documentation

brochure_sp-mp.pdf

Katarzyna Nazarewicz

Country manager

Katarzyna Nazarewicz

+48 797 701 027

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Located inside a tissue culture incubator, it is capable of switching any one of the wells on any of six E-Plates to the RTCA Analyzer for impedance measurement.

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The RTCA DP Analyzer has three integrated stations for E-Plates 16 or CIM-Plates 16.

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xCELLigence DP – Agilent technologies