Spatial biology is a rapidly evolving discipline that advances human health by leveraging imaging technologies. It encompasses research activities ranging from whole-transcriptome profiling to clinically impactful single-protein biomarker tests.
Understanding cell-cell interactions within the tumor-immune microenvironment is crucial for advancing cancer therapies. Macrophages show highly variable roles in tumor progression and response, yet the drivers of this complexity remain unclear.
Researchers using iPSC-derived neurons and glia for ALS models have found that WOLF’s gentle, low-pressure sorting preserves fragile cells’ viability and function—unlike traditional droplet sorters.
Phase contrast and fluorescence microscopy reveals structural and molecular details in cells. Lumascope microscopes are ideally suited for research that requires both, for example this cancer-related study.
What if studying membrane proteins didn’t have to be so hard? Discover how a breakthrough technique is making fragile, complex proteins easier to analyze — no purification, no immobilization, just real results.
Single-cell biology has transformed our ability to uncover cellular diversity and dynamic behavior within complex tissues that are otherwise masked in population-level analyses.
Join us for an exclusive webinar in collaboration with Accela exploring the Beacon platform and discover how cutting-edge single-cell technology is accelerating the discovery and development of novel therapeutics.
See how high-resolution multiplex immunofluorescence imaging can elucidate the important role the immune system plays in health, disease, and drug development.
This presentation introduces the VERLO™ Image-Guided Cell Sorter from NanoCellect. VERLO integrates advanced image-guidance technology with cell sorting, enhancing precision and efficiency.
They developed MDG1015 — CD8⁺ TCR-T cells armored with a PD1-41BB costimulatory switch protein (CSP) that converts PD-L1–mediated inhibition into activation. In vitro, they selectively kill PD-L1⁺ tumor cells while sparing non-target cells.
The NanoCellect VERLO Image-Guided Cell Sorter is mentioned in the attached Nature Reviews Bioengineering paper (Ding et al., 2025) reviewing commercially available Image-Activated Cell Sorting systems.
In this application note, we outline the approach to study interactions between small molecules
and membrane proteins using Flow Induced Dispersion Analysis (FIDA).