Discover
Introducing Synlight-Pure — Ultra-High Precision Photolabeling for Nanoscopic Proteomic Discovery
The webinar is demonstrating how microscopy-guided, patterned light activation enables protein purification directly from visually defined subcellular structures.
April 22, 2026
Introducing Orion HT
The New Standard for Spatial Biomarker Development in Translational and Clinical Research
April 20, 2026
Molecular and Spatial Drivers of Immunotherapy Response in Mucosal Melanoma
Findings suggest that distinct genomic features, tumor states, and microenvironments differentiate ICB response and progression in MM, highlighting key tumor-intrinsic and microenvironmental factors associated with prognosis.
March 18, 2026
Comparing Microscoop with Proximity Labeling Techniques APEX2 and BioID
Discover how Microscoop, APEX2, and BioID offer unique advantages for mapping protein-protein interactions—whether in fixed tissue or live cells. Learn which method fits your proteomics research best!
February 23, 2026
Functional, Fast, and Unbiased TCR Discovery with Bruker’s Optofluidic Platform
Identifying antigen specific T-cell receptors (TCRs) is critical for advancing TCR-T therapies, vaccines, and infectious disease research. Yet, traditional peptide-MHC tetramer/dextramer sorting only tells part of the story.
January 23, 2026
Perfusion: The Beating Heart of Single-Cell Biology and Cancer Immunotherapy
Single-cell biology has transformed our ability to uncover cellular diversity and dynamic behavior within complex tissues that are otherwise masked in population-level analyses.
November 24, 2025
PHF19 drives the formation of PRC2 clusters to enhance motility in TNBC cells
This study investigates the subnuclear organization of the Polycomb repressive complex 2 (PRC2) in triple-negative breast cancer (TNBC) cells, combining in situ proteomics, high-resolution imaging, and functional genomics.
April 14, 2026
Introducing IVM-FS: Real-Time Cellular Insightsinto Rats and Other Medium-Sized Animals
Rats are increasingly valued for intravital imaging due to their larger body size and organ systems, which enable more precise surgical preparation, stable window implantation, and repeated long-term imaging - advantages over mice.
March 3, 2026
Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL
T-cell exhaustion contributes to immunotherapy failure in chronic lymphocytic leukemia (CLL). T cells from CLL patients' blood, bone marrow, and lymph nodes were analyzed using single-cell RNA sequencing, mass cytometry, and tissue imaging.
February 12, 2026
The Path to Clinical Relevance: Moving from Spatial Transcriptomics to Protein Profiling
Spatial biology is a rapidly evolving discipline that advances human health by leveraging imaging technologies. It encompasses research activities ranging from whole-transcriptome profiling to clinically impactful single-protein biomarker tests.
December 2, 2025
Preclinical Development for Therapy of Hard-to-Treat PD-L1-Positive Solid Tumors
They developed MDG1015 — CD8⁺ TCR-T cells armored with a PD1-41BB costimulatory switch protein (CSP) that converts PD-L1–mediated inhibition into activation. In vitro, they selectively kill PD-L1⁺ tumor cells while sparing non-target cells.
November 17, 2025
Microscopy-guided subcellular proteomic discovery by high-speed ultra-content photo-biotinylation
Syncell developed a method combining microscopy, photo-biotinylation, and mass spectrometry, enabling high-resolution mapping of proteins in subcellular regions, accelerating discoveries in spatial proteomics research.
March 23, 2026
Combining GrowDex and spheroONE for automated and highly reproducible 3D cell culture workflows
This application note demonstrates the compatibility of spheroONE and GrowDex to automate 3D cell culture workflows. spheroONE is a nanoliter dispenser enabling sorting and isolation of spheroids and organoids.
February 25, 2026
Low-Cost Small Molecules to Replace bFGF
Low-Cost Small Molecules to Replace bFGF, Enabling Stable and Scalable Cell Growth Benefitting R&D and Industrial Application
February 4, 2026
Genotype-Specific Macrophage Programs in the NSCLC Microenvironment
Understanding cell-cell interactions within the tumor-immune microenvironment is crucial for advancing cancer therapies. Macrophages show highly variable roles in tumor progression and response, yet the drivers of this complexity remain unclear.
November 26, 2025