Discover

Introducing IVM-FS: Real-Time Cellular Insightsinto Rats and Other Medium-Sized Animals

Rats are increasingly valued for intravital imaging due to their larger body size and organ systems, which enable more precise surgical preparation, stable window implantation, and repeated long-term imaging - advantages over mice.

March 3, 2026

Application
Product news

Combining GrowDex® and spheroONE for automated and highly reproducible 3D cell culture workflows

This application note demonstrates the compatibility of spheroONE and GrowDex® to automate 3D cell culture workflows. spheroONE is a nanoliter dispenser enabling sorting and isolation of spheroids and organoids.

February 25, 2026

Application

Low-Cost Small Molecules to Replace bFGF

Low-Cost Small Molecules to Replace bFGF, Enabling Stable and Scalable Cell Growth Benefitting R&D and Industrial Application

February 4, 2026

Technical breakthrough

Genotype-Specific Macrophage Programs in the NSCLC Microenvironment

Understanding cell-cell interactions within the tumor-immune microenvironment is crucial for advancing cancer therapies. Macrophages show highly variable roles in tumor progression and response, yet the drivers of this complexity remain unclear.

November 26, 2025

Scientific paper

Gentle Cell Sorting Advancing ALS Research

Researchers using iPSC-derived neurons and glia for ALS models have found that WOLF’s gentle, low-pressure sorting preserves fragile cells’ viability and function—unlike traditional droplet sorters.

October 15, 2025

Technical breakthrough

Applications: Phase Contrast and Fluorescence Microscopy

Phase contrast and fluorescence microscopy reveals structural and molecular details in cells. Lumascope microscopes are ideally suited for research that requires both, for example this cancer-related study.

August 18, 2025

Comparing Microscoop® with Proximity Labeling Techniques APEX2 and BioID

Discover how Microscoop®, APEX2, and BioID offer unique advantages for mapping protein-protein interactions—whether in fixed tissue or live cells. Learn which method fits your proteomics research best!

February 23, 2026

Application

Functional, Fast, and Unbiased TCR Discovery with Bruker’s Optofluidic Platform

Identifying antigen specific T-cell receptors (TCRs) is critical for advancing TCR-T therapies, vaccines, and infectious disease research. Yet, traditional peptide-MHC tetramer/dextramer sorting only tells part of the story.

January 23, 2026

Application

Perfusion: The Beating Heart of Single-Cell Biology and Cancer Immunotherapy

Single-cell biology has transformed our ability to uncover cellular diversity and dynamic behavior within complex tissues that are otherwise masked in population-level analyses.

November 24, 2025

Application

Webinar recording: Unleashing the Power of Single Cell Multi-Omics, Cell Therapy – with Beacon Discovery

Join us for an exclusive webinar in collaboration with Accela exploring the Beacon platform and discover how cutting-edge single-cell technology is accelerating the discovery and development of novel therapeutics.

October 10, 2025

Webinar

IsoSpark in HIV research: quantitation of proteins in the culture supernatants.

Exciting example of use 22-plex antibody with the IsoPlexis Human Adaptive Immune Panel (Bruker Cellular Analysis) in HIV research.

June 12, 2025

Application

Integrative multi-omics reveals a regulatory and exhausted T-cell landscape in CLL

T-cell exhaustion contributes to immunotherapy failure in chronic lymphocytic leukemia (CLL). T cells from CLL patients' blood, bone marrow, and lymph nodes were analyzed using single-cell RNA sequencing, mass cytometry, and tissue imaging.

February 12, 2026

Scientific paper

The Path to Clinical Relevance: Moving from Spatial Transcriptomics to Protein Profiling

Spatial biology is a rapidly evolving discipline that advances human health by leveraging imaging technologies. It encompasses research activities ranging from whole-transcriptome profiling to clinically impactful single-protein biomarker tests.

December 2, 2025

Application

Preclinical Development for Therapy of Hard-to-Treat PD-L1-Positive Solid Tumors

They developed MDG1015 — CD8⁺ TCR-T cells armored with a PD1-41BB costimulatory switch protein (CSP) that converts PD-L1–mediated inhibition into activation. In vitro, they selectively kill PD-L1⁺ tumor cells while sparing non-target cells.

November 17, 2025

Scientific paper

Image-activated cell sorting

The NanoCellect VERLO Image-Guided Cell Sorter is mentioned in the attached Nature Reviews Bioengineering paper (Ding et al., 2025) reviewing commercially available Image-Activated Cell Sorting systems.

September 16, 2025

Scientific paper

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